Well, I could see how Dreamweaver could be used as a tool to help with making the various skins, but I haven't seen anything that would create the whole set up for you. I did a few google searches this morning and still didn't come across anything.
When I'm creating a new skin, I create my html for the layout, and then divide it up into the header and footer and then use a dummy file with content in it so I can be sure it all works out before I put it up. And these parts of the skinning could be done in dreamweaver. But the actual setup of the skins still needs to have files created and uploaded.
In case you haven't seen the tutorial that Robyn and I used to skin our sites, Amy's site is the place to go -
Domesticat's Skinning Tutorial. I created a companion tutorial for using with MT -
Working with Amy's How to Skin Your Site and the Movable Type journalling software. And even though the setup is daunting, its so easy to add skins after you get it all set up!

Kristine